Successful cream horns pair complementary fillings that enhance rather than compete with each other. Classic combinations like coffee and chocolate work because coffee's bitterness balances chocolate's sweetness. Citrus cuts through rich creamy fillings, providing necessary acidity. When creating flavor pairings, consider contrast in both taste and texture - smooth cream with fruit gel, rich ganache with bright curd. Avoid pairing flavors that sit in the same taste profile, which can seem monotonous. Test flavor combinations separately before committing to ensure they enhance each other. The pastry itself is buttery and rich, so fillings should provide contrast rather than adding more richness.